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These cells either aggregatein nests or are scattered through the entire thickness of theepidermis (Fig. This is due to vasodilator action thatprecedes the saluretic action

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After incubation with avidin-biotin-peroxidase complex, the posi-tive response was then visualized with diaminobenzidine (DAB) solution{brown-coloredreaction).

The detailedrelationship is seen at the electron microscope level. In case of no response, muromonab CD3/ATG is given as rescue therapy or the antibodiesare combined with steroids.

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